Monday, September 27, 2010

Skin Prick Testing

This test measures specific IgE attached to Mast cells in the skin

Allergen solutions for skin prick testing: PONI F

  • Positive control (histamine)
  • Occupational allergens (ammonium persulphate, platinum salts, antibiotics, and latex)
  • Negative control (diluent)
  • Inhaled allergens (house dust mite (HDM), grass pollen, cat dander, dog hair)
  • Food allergens

Disadvantages of skin prick test: FISH

  • Food allergens (less standardized), less reliable than inhaled allergens
  • Itching
  • Skin conditions (eczema or dermatographism) interfere with interpretation
  • Histamine antagonists (antihistamines) suppress skin reaction

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