Fibroadenoma
Fibroadenomas, which are generally firm, smooth, and round, can be readily moved under the skin and are often described as feeling similar to marbles. Typically the masses measure from 1 to 3 centimeters in size, but occasionally they may grow much larger, in which case they are termed giant fibroadenomas. Fibroadenomas, which arise from the intralobular stroma, are solid and consist of a combination of glandular and fibrous tissues. The tumors are usually painless and present no symptoms, typically being discovered by young women only due to self-examination. In older women, fibroadenomas are often less palpable and may first be discovered during a routine mammogram.
Fibroadenomas showing circumscribed margins, even distribution of epithelial and stromal components and low stromal cellularity.
-Low power scanning of Fibroadenoma :
# Use low power scanning to determine:
# The stroma can be cellular particularly in younger patient's lesions - but it's usually uniform
# The occasional stromal mitosis is acceptable in a younger patient's lesion but take advice
# Uneven stromal cellularity in a core biopsy may be a pointer to a Phyllodes Tumour
You can suspect Phyllodes Tumour if:
* Patient older than 40 years
* Lesion larger than 4 cm
* History of recent growth
Fibroadenomas showing circumscribed margins, even distribution of epithelial and stromal components and low stromal cellularity.
-Low power scanning of Fibroadenoma :
# Use low power scanning to determine:
- the basic pattern - pericanalicular or intracanalicular
- edge of lesion (pushing or infiltrative) - should be pushing
- balance between stroma and epithelium - should be even
- to pick out areas of stromal hypercellularity
# The stroma can be cellular particularly in younger patient's lesions - but it's usually uniform
# The occasional stromal mitosis is acceptable in a younger patient's lesion but take advice
# Uneven stromal cellularity in a core biopsy may be a pointer to a Phyllodes Tumour
You can suspect Phyllodes Tumour if:
* Patient older than 40 years
* Lesion larger than 4 cm
* History of recent growth
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