Pediatric Measurements

Pathophysiology of Disease An Introduction to Clinical Medicine, 6th

* Publisher: McGraw-Hill Medical
* Number Of Pages: 752
* Publication Date: 2009-10-20
* ISBN-10 / ASIN: 0071621679
* ISBN-13 / EAN: 9780071621670



A complete case-based review of the essentials of pathophysiology – covering all major organs and systems

This trusted text introduces you to clinical medicine by reviewing the pathophysiologic basis of the signs and symptoms of 100 diseases commonly encountered in medical practice. Each chapter first describes normal function of a major organ or organ system, then turns attention to the pathology and disordered physiology, including the role of genetics, immunology, and infection in pathogenesis. Underlying disease mechanisms are described, along with their systems, signs, and symptoms, and the way these mechanisms themselves determine the most effective treatment.

This unique interweaving of physiological and pathological concepts will put you on the path towards thinking about signs and symptoms in terms of their pathologic basis, giving you an understanding of the “whys” behind both illness and treatment.

Features


* NEW full-color presentation
* 111 case studies (22 new ones) provide an opportunity for you to test your understanding of the pathophysiology of each clinical entity discussed
* A complete chapter devoted to detailed analyses of the cases
* “Checkpoint” review questions appear throughout every chapter
* Numerous tables and diagrams encapsulate important information
* References for each chapter topic
* NEW sections in the chapters on liver disease and inflammatory rheumatic diseases and a completely rewritten chapter on male reproductive tract disorders

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Subclavian Steal Syndrome

A 68-year-old man with hypertension, dyslipidemia, and diabetes mellitus presented with dizziness, presyncope, and blurring of vision that occurred when he used his left hand while gardening. He reported no history of coronary or vascular disease.

A physical examination was notable for blood pressures of 150/70 mm Hg in the right arm and 80/60 mm Hg in the left arm, with weak brachial and radial pulses on the left side. The cardiac examination revealed an audible S4, a bruit in the right carotid artery, and a thrill and bruit over the left subclavian artery.

Angiography showed a severe proximal left subclavian stenosis (arrow), with retrograde flow in the left vertebral artery. This pattern of flow, and the resulting clinical symptoms, is known as the subclavian steal syndrome.
The patient underwent successful stenting of the subclavian stenosis. He began receiving medical therapy for his peripheral vascular disease, consisting of aspirin, a high-dose statin, and an angiotensin converting enzyme inhibitor (ACEI). At a follow-up visit 3 months later, there was clinically significant improvement in symptoms, including a difference of 15 mm Hg in systolic blood pressure between the two arms and no subclavian bruit.

C. D. Review of Skeletal Muscle Tissue

This Video is recorded off a cd-room. there may be some background noises, SORRY for that