Pachyderma due to scabies
A 65-year-old white man with a history of
multiple myeloma presented with
thick, leathery, gray skin of the torso and extremities.
Panel A shows the left axilla. The patient reported intense pruritus and thickening of his skin during the previous 6 months, despite treatment with oral and topical corticosteroids. Because of chronic immunosuppression due to his underlying malignant condition, a specimen obtained from scrapings of the skin was prepared and examined. It showed scabies mites, eggs, and scybala (fecal pellets)
(Panel B), which confirmed a diagnosis of crusted scabies.
The patient was treated with
oral ivermectin and topical permethrin, with noticeable improvement within 1 month; subsequently, the patient was lost to follow-up.
Crusted scabies is a rare variant of scabies and occurs most commonly in immunosuppressed patients.
It presents as: erythematous or gray hyperkeratotic patches or plaques that can resemble the hide of a pachyderm (elephant, rhinoceros, or hippopotamus);
“pachyderma” refers to thick skin, like that of a pachyderm. Patients with crusted scabies have a very high burden of mites and are extremely infectious. Thus, a prompt diagnosis is needed to avoid transmission to others. No such transmission was documented in this case.
Labels: DERMATOLOGY, HEAMATOLOGY, MEDICAL PHOTOS/PICTURES/IMAGES, ONCOLOGY